The study of therapy to diarrhea symptoms by the bile acid sequestrants

Phase 2

Recruiting

• Conditions: IBS-D or functional diarrhea

• Registration Number: JPRN-jRCTs031180044
• Lead Sponsor: Misawa Noboru

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-11-27
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

(1) Patients who are diagnosed IBS-D or functional diarrhea by ROME criteria and have treatment for the diarrhea within 4 weeks before entry
(2) Patients who have more than three defecation or more than bristol score 6 per day
(3) Patients who are excluded mechanical disorders by colonoscopy within five years
(4) Patients who are 20 years old or over and under 80

Exclusion Criteria

(1) Patients who have severe complications
(2) Patients who had colestimide within 4 weeks before entry
(3) Patients who have history of colestimide allergies
(4) Patients who are biliary obstruction
(5) Patients who are intestinal obstruction
(6) Patients who have narrowing of colon lumen
(7) Patients who have diverticular disease of intestine
(8) Patients who have difficulty of swallowing
(9) Patients who have hemorrhoid
(10) Patients who have or had gastrointestinal ulcer
(11) Patients who have bleeding tendency
(12) Patients who have particular drug
(13) Patients who have fewer than bristol score 2
(14) Patients who have severe psychiatric disease
(15) Patients who have current evidence of abuse of drugs or alcohol
(16) Patients who have new therapy for diarrhea within 4 weeks before entry
(17) Patients who had taken new drug therapy within 4 weeks before entry
(18) Patients who are judged as inadequately for study entry

Study & Design

• Study Type: Interventional
• Study Design: Not specified