Comparative Study of Metformin Versus Doxycycline in Moderate to Severe Adult Acne Vulgaris Patients.
- Registration Number
- NCT06252194
- Lead Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
- Brief Summary
The goal of this clinical trial is to compare the effect of doxycycline and metformin in treatment of acne vulgaris patients. The main question is aimed to answer is whether metformin is more effective than doxycycline in treatment of acne vulgaris patient or not.
Patients will be asked to take doxycycline along with tropical treatment in one group and metformin along with tropical treatment in another group.
Researcher will compare the clinical improvement in two groups.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Newly diagnosed moderate and severe AV patients diagnosed by a dermatologist
Exclusion Criteria
- Patients receiving topical retinoids within last two months
- Pregnancy and lactation
- History of corticosteroids intake
- Suffering from malignancy or any cosmetic induced acne
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Group A Metformin and doxycycline Metformin 500 mg twice daily along with topical retinoids for 12 weeks Group B Metformin and doxycycline Doxycycline 100 mg twice daily along with topical retinoids for 12 weeks
- Primary Outcome Measures
Name Time Method Global Acne Grading System (GAGS) Score 12 weeks Acne Vulgaris Severity assesment by GAGS score
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
BSMMU
🇧🇩Dhaka, Bangladesh