Tailored Hospital-based Risk Reduction to Impede Vascular Events After Stroke
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Stroke
- Sponsor
- Medical University of South Carolina
- Enrollment
- 400
- Locations
- 3
- Primary Endpoint
- Reduction in systolic blood pressure
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
The purpose of this study is to determine whether a culturally-sensitive multipronged post-discharge intervention can significantly reduce blood pressure, enhance achievement of guideline recommended targets for risk factor control, and lower recurrent vascular events in a low-income and middle-income (LMIC). The study will have 2 Phases - a qualitative phase (Phase 1) lasting less than one year involving development of the intervention through focus group methodologies and structured interviews, and a clinical trial phase (Phase 2)lasting 3 years involving a randomized trial testing the efficacy of the intervention.
Detailed Description
This research seeks to develop an effective and sustainable way of reducing the devastating and deadly impact of stroke in a low-income region of the world with poor medical infrastructure. It will do so by focusing on improving the treatment of the condition most closely tied to stroke, hypertension, using novel methods that incorporate the input of the local community. If successful, the strategy could serve as a ready model to be adapted by decision-makers in other under-resourced areas for lessening the burden of stroke(and other major public health challenges).
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age ≥ 18 years Stroke within one year access to mobile phone.
Exclusion Criteria
- •Any medical condition that would limit participation in follow up assessments, Severe cognitive impairment/dementia (MMSE ≤24) Severe global disability (modified Rankin Score ≥ 3).
Outcomes
Primary Outcomes
Reduction in systolic blood pressure
Time Frame: 1 year
Reduction in systolic blood pressure at one year post-discharge in stroke patients.
Secondary Outcomes
- Reduced rate of subsequent primary vascular event(1 year)