The Enhancement Effect of Low-Level Laser Therapy for Muscle Training with Combined Neuromuscular Electrical Stimulation and Blood Flow Restriction
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- Myoton
研究概览
简要总结
Blood flow restriction training (BFR) with neuromuscular stimulation (NMES) is employed for individuals with limited mobility and joint issues. However, this approach is highly susceptible to muscle fatigue, despite its potential beneficial effects on muscle strength. Recently, there has been growing interest in using low-level laser therapy (LLLT) to address muscle fatigue. LLLT, known for improving microcirculation and mitochondrial function, shows promise in alleviating enhanced muscle fatigue associated with combined BFR and NMES training. Despite these positive effects, there is limited knowledge about the short-term training impact of combined BFR and NMES with LLLT preconditioning. This project aims to investigate whether the photobiomodulation effects of LLLT could further enhance the training benefits of combined BFR and NMES. The study will employ an integrated analysis of decomposition surface EMG, EEG, and mechanomyogram to explore the behavior and neuromuscular mechanisms underlying the training benefits. If additional benefits are identified, LLLT pre-conditioning is recommended to enhance the use of combined BFR and NMES.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 40 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy adults aged 20-40, without a diagnosis of cardiovascular or neuromusculoskeletal diseases.
- •Normal vision range after visual correction.
排除标准
- •Exclude students who have a teacher-student relationship with the principal investigator to ensure the participants' autonomy.
- •History of brain injury, stroke, spinal cord injury, or other neuromuscular-related conditions.
- •Contraindications for laser therapy: pregnancy, malignant tumor tissues, bleeding areas, and photosensitive skin regions.
- •Presence of any contraindications for blood flow restriction training, such as a history of injury or strain in the non-dominant arm's biceps, deep vein thrombosis or venous occlusion in the non-dominant arm, acute unstable fractures in the non-dominant arm, acute regional infections in the non-dominant arm, severe peripheral arterial occlusive disease in the non-dominant arm, complete lymphatic obstruction in the non-dominant arm, and edema due to acute pulmonary edema or congestive heart failure in the non-dominant arm.
研究组 & 干预措施
LLLT+BFR+NMES
LLLT: low-level laser therapy BFR: blood flow restriction NMES:neuromuscular Electrical Stimulation
35 min/time, 3 times/weeks, 3 weeks
干预措施: Low Level Laser Therapy (Device)
LLLT+BFR+NMES
LLLT: low-level laser therapy BFR: blood flow restriction NMES:neuromuscular Electrical Stimulation
35 min/time, 3 times/weeks, 3 weeks
干预措施: blood flow restriction (Device)
LLLT+BFR+NMES
LLLT: low-level laser therapy BFR: blood flow restriction NMES:neuromuscular Electrical Stimulation
35 min/time, 3 times/weeks, 3 weeks
干预措施: Neuromuscular Electrical Stimulation (Device)
BFR+NMES
BFR: blood flow restriction NMES:Neuromuscular Electrical Stimulation
35 min/time, 3 times/weeks, 3 weeks
干预措施: blood flow restriction (Device)
BFR+NMES
BFR: blood flow restriction NMES:Neuromuscular Electrical Stimulation
35 min/time, 3 times/weeks, 3 weeks
干预措施: Neuromuscular Electrical Stimulation (Device)
结局指标
主要结局
Myoton
时间窗: before training, 1week of training, 2 weeks of training, at the end of 3 weeks training
Non-dominant hand extensor digitorum muscle belly parameters of static mechanical properties of muscles (Tone, Stiffness, Relaxation, Creep, etc.)
Mechanomyogram
时间窗: before training, 1week of training, 2 weeks of training, at the end of 3 weeks training
Recording of extensor digitorum muscle microshock waves during contraction
Multi-electrode surface EMG
时间窗: before training, at the end of 3 weeks training
Record muscle activity during contraction
Dynamometer System
时间窗: before training, 1week of training, 2 weeks of training, at the end of 3 weeks training
Measurement to track the degree of force applied by a non-dominant hand.
次要结局
未报告次要终点
