The Five-year Pattern of Red Blood Cell Transfusion and Clinical Outcome in Patients Undergoing Percutaneous Coronary Intervention: A Korean Nationwide Longitudinal Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 48,786
- 试验地点
- 1
- 主要终点
- Incidence density of transfusion
研究概览
简要总结
A nationwide retrospective cohort study. To investigate the long-term patterns of transfusion and clinical outcomes of patients undergoing PCI.
详细描述
A nationwide retrospective cohort study. Transfusion after PCI may increase a risk, but the long term effects after red blood cell transfusion is known. Longitudinal data is collected from administrative claims in the National Healthcare Insurance Service of Korea. All Korean patient date undergoing PCI inserting stent from January 1, 2011 to December 31, 2011 is extracted. Clinical outcomes until December 31, 2016 is investigated.
Primary outcome is the incidence density of red blood cell transfusion. Secondary outcomes are the association of transfusion with major adverse clinical event (MACE) consisting all-cause death, revascularization, critically ill cardiovascular status, or stroke.
Incidence density and time-dependent Cox proportional hazard regression is statistically analyzed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All Korean patients undergoing PCI using stent from January 1, 2011 to December 31, 2011
排除标准
- •Patients without any stent insertion
结局指标
主要结局
Incidence density of transfusion
时间窗: 5 years
5-year incidence density of red blood cell transfusion
次要结局
- Incidence density of MACE(5 years)
研究者
Jin-Ho Choi
MD, PhD, Professor
Samsung Medical Center