Histopathology of Female Urethral Strictures
- Conditions
- Health Condition 1: N359- Urethral stricture, unspecified
- Registration Number
- CTRI/2024/01/061636
- Lead Sponsor
- Department of Urology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Females aged 18 years or above with urethral stricture disease confirmed by uroflowmetry and cystoscopy.
2.Females who undergo a dorsal onlay buccal mucosal graft urethroplasty.
3.Written informed consent.
1.Patients who have undergone surgery for urethral stricture disease previously
2.Patients in whom ventral BMGU is performed.
3.Patients with STDs
4.Patients with genitourinary anomalies
5.Patients who have had surgery for hypertrophy of the bladder neck
6.Patients who have had radiation to the pelvis
7.Patients with bladder malignancies
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method a)Evaluation for epithelial hyperplasia and cell typeTimepoint: 10 days
- Secondary Outcome Measures
Name Time Method a)To evaluate the presence of mucosal oedema <br/ ><br>b)To evaluate the degree of fibroblast/inflammatory cell infiltrate <br/ ><br>c)To evaluate the elastin fibre distribution. <br/ ><br>Timepoint: baseline, 4 weeks