SLCTR/2016/002尚未招募3 期
Addition of Propranolol in Resistant Arterial Hypertension Treatment - A randomized clinical trial
ational Research Council, Sri Lanka0 个研究点目标入组 120 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 120
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Age between 18-75 years
- •2. Resistant hypertension is defined as casual blood pressure during clinical examination of more than 140/90 mmHg (a mean of the 2nd and 3rd measurements during a single examination, at least 3 min apart) despite treatment with a multidrug combination consisting of a diuretic and ACEI/ARB, centrally acting drug, alpha blocker or calcium channel blocker
- •3. Blood pressure >140/90mmHg in patients below 60 years and >150/90mmHg if above 60 years
排除标准
- •1. Systolic blood pressure > 220mmHg requiring immediate adjustments to therapy
- •2. Moderate to severe renal insufficiency (acute or chronic) with glomerular filtration rate of less than 30 ml/min ,
- •3. Active bronchospastic disorders
- •4. Heart failure class III and IV
- •5. Severe bradycardia(HR<50bpm)
- •6. AV block 2 and 3 degrees
- •7. Women who are lactating or pregnant ( a pregnancy test will be carried out during the initial examination)
- •8. History of hypersensitivity to any of the drugs under study
- •9. Current use of beta blockers
研究者
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