Treating Vitamin D Deficiency on Post CABG Atrial Fibrillatio

Phase 2

Conditions: Condition 1: . Condition 2: vitamin d deficiency. Condition 3: atrial fibrillation after the surgery.
Vitamin D deficiency, unspecified
Atrial fibrillation and flutter

Registration Number: IRCT20170620034666N1

Lead Sponsor: isfahan university of medical sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 400

Inclusion Criteria

b)Hypovitaminosis D (serum 25(OH) Vitamin D< 20 ng/ml)
c)Written and informed consent to participate in this project
CABG indications like trivessel occlusion
no emergency intervention needed

Exclusion Criteria

e)Hyperparathyroidism (PTH>upper normal limit according to lab reference range)
f)Liver failure (any positive past medical history or AST and/or ALT 2 times more than normal upper limit)
g)Renal Failure (any positive past medical history or Glomerular filtration rate <60 calculated with MDRD eGFR formula of Qx medical application )
h)Any prior history of diagnosed cancer, rheumatologic and immunologic disorders
b)BMI>30 kg/m2
vitamin d toxicity
hypercalcemia

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Occurrence of atrial fibrillation after the surgery. Timepoint: till 7 days after the surgery 24 hours in ICU. Method of measurement: electrocardiography.;Number of atrial fibrillation. Timepoint: till 7 days after the surgery 24 hours in ICU. Method of measurement: electrocardiography.;Left ventricular function. Timepoint: before starting taking drugs, before surgery, before discharging from hospital. Method of measurement: echocardiography.

Secondary Outcome Measures

Name	Time	Method
eft ventricular function after 1 year. Timepoint: before starting taking drugs, before surgery, before discharge and 1 year after the surgery. Method of measurement: echocardiography.