Correlation of venous excess ultrasound score with acute kidney injury in patients with left heart failure
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Assess the correlation between serial VEXUS
研究概览
简要总结
Acute left heart failure is associated with volume overload or venous congestion. Fluid overload leads to venous congestion, thereby increasing venous pressure and theoretically increasing the backpressure and reducing renal blood flow, and since kidneys are encapsulated organs it might make them more sensitive to this effect. Apart from increased mortality, venous congestion can cause end- organ damage, thereby increasing the incidence of acute kidney injury (AKI), length of stay in ICU, and duration of mechanical ventilation. Clinical signs of fluid overload like peripheral edema and ascites are poor indicators of fluid overload in the ICU setup. In view of lack of reliable peripheral signs of venous congestion, objective determination of the same is the need of the hour to aid key clinical decisions like fluid restriction and diuretic administration.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 90.00 Year(s)(—)
- 性别
- All
入选标准
- •1 Age above 18 years 2 Patients presenting to ICU with Left Heart failure with reduced ejection fraction EF less than 45 percent 3 Patients meeting NT pro BNP cut off for diagnosis of heart failure age less than 50 years 450 pg per ml age 50 to 75 years 900 pg per ml age greater than 75 years 1800 pg per ml 4 Patients having AKI as per KDIGO criteria.
排除标准
- •1 Patients having chronic liver diseases with portal hypertension 2 IVC thrombosis 3 Patients having COPD with cor pulmonale 4 Major valvular abnormalities 5 Heart failure due to arrythmias 6 Pregnant females 7 AKI due to sepsis or drug induced.
结局指标
主要结局
Assess the correlation between serial VEXUS
时间窗: 48 hours
score and AKI in patients with heart failure
时间窗: 48 hours
次要结局
- Assess correlation between VEXUS score &(fluid balance)
研究者
Dr Milind Manvar
Medanta, The Medicity, Gurgaon
