Comparing Effectiveness of combination of magnesium oxide and potassium citrate with potassium citrate in children with urolithiasis
- Conditions
- nephrolythiasis.Calculus of kidney and ureter
- Registration Number
- IRCT2014041217234N1
- Lead Sponsor
- Vice chancellor for research, Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
All children:
1.Under 15 years of age with sonographic diagnosis of stone.
2.With stones greater than 2 mm diameter; Microlithiasis below 2 mm due to the possible technical errors and less clinical value will be ignored.
3.Who completed informed consent form.
Exclusion criteria:
1.Presence of side effects (such as gastritis, gastrointestinal complications due to potassium citrate, sluggishness, lethargy, muscle weakness and diarrhea due to magnesium which drug would be discontinued in this case)
2.Comorbidities which influence tubular secretion such as renal tubular acidosis, pyelonephritis and obstructive uropathy.
3.Not referring in order to sonography and laboratory tests
4.Diagnosed cases who are under medication therapy
5.Over 15 years old age
6.Stones with 2 mm diameter or less
7.Patients need treatment other than conventional therapies such as patients who need hydrochlorothiazide or cystinuria patients who need penicillamine.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method At least 1 millimeter change in stone size during treatment. Timepoint: First day and end of third month. Method of measurement: Sonography.
- Secondary Outcome Measures
Name Time Method Drug side effects such as gastritis and other GI complications due to potassium citrate and muscle weakness due to magnesium. Timepoint: Any time during study. Method of measurement: History and physical examination.