Addition of Silver Nanoparticles to a Orthodontic Primer in Preventing Enamel Demineralization Adjacent Brackets

Phase 3

• Conditions: Tooth Demineralization

• Registration Number: NCT02400957
• Lead Sponsor: Universidad Autonoma de San Luis Potosí

Brief Summary

Evaluate the effectiveness of silver nanoparticles incorporated into the primer orthodontic Transbond XT in preventing enamel demineralization adjacent to brackets.

Detailed Description

Randomized, split mouth, double-blind, placebo controlled trial. Half of the mouth was applied silver nanoparticles incorporated into the primer orthodontic Transbond XT and the other half with primer-bond as placebo. Evaluate the effectiveness with Diagnodent - pen in preventing enamel demineralization adjacent to brackets.

Study Timeline

• Study Start: 2014-09
• Status Verified: 2015-03
• Study First Submitted: 2015-03-24
• Study First Submitted QC: 2015-03-26
• Last Update Submitted: 2015-03-26
• Study First Posted: 2015-03-27
• Last Update Posted: 2015-03-27
• Primary Completion: 2015-05
• Study Completion: 2015-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Patients candidates for orthodontic treatment.

Exclusion Criteria

• Patients with O.D 11 and / or 21 absent.

  • Patients who present dentures of any kind in OD 11 and 21.
  • Patients presenting endodontic OD 11 and 21.
  • Patients presenting data gingivitis day cementing brackets.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
enamel demineralization (Diagnodent - pen evaluation)	8 weeks

Trial Locations

Locations (1)

Gabriela Moreno Meraz; 🇲🇽 San Luis Potosi, Mexico