Beta-Blockers in Heart Failure: Pharmacy-level Intervention Comparison
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 220
- 试验地点
- 2
- 主要终点
- Rate of Adherence to Guideline Prescription
研究概览
简要总结
The overall objective of the proposed pilot study is to begin evaluation of two methods for promoting adherence to guidelines for beta-blocker therapy in heart failure. The design includes site level baseline measurement, feedback, remeasurement after six months, and randomized (by site) comparison samples. The setting is VA sites, with intervention directed at the pharmacy.
详细描述
Current evidence-based guidelines in VA recommend one of three beta-blockers (carvedilol, metoprolol succinate, or bisoprolol) that have been shown to reduce mortality in heart failure patients with systolic dysfunction, with recommended target doses. However, Pharmacy Benefits Management (PBM) data indicate that prescribing for beta-blockers in heart failure patients that is not in accordance with guidelines is substantial, both in terms of the agent selected and the dose. Sites will be recruited and randomized to two different intensities of intervention to promote adherence to guidelines.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Males and females
排除标准
- 未提供
研究组 & 干预措施
Level 1: site-specific information
provide site-specific information on nonadherence
干预措施: Level 1: (provide site-specifi information) (Other)
Level 2: site-, patient-specific info
provide site- and patient-specific information on nonadherence
干预措施: Level 2 (Provide site- and patient-specific information) (Other)
结局指标
主要结局
Rate of Adherence to Guideline Prescription
时间窗: 6 months
full adherence to guideline medication and dose
次要结局
- Progress Toward Adherence to Guideline Prescription(6 months)