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Clinical Trials/NCT01002456
NCT01002456
Completed
Not Applicable

Beta-Blockers in Heart Failure: Pharmacy-level Intervention Comparison

US Department of Veterans Affairs1 site in 1 country220 target enrollmentOctober 2009
ConditionsHeart Failure

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Heart Failure
Sponsor
US Department of Veterans Affairs
Enrollment
220
Locations
1
Primary Endpoint
Rate of Adherence to Guideline Prescription
Status
Completed
Last Updated
11 years ago

Overview

Brief Summary

The overall objective of the proposed pilot study is to begin evaluation of two methods for promoting adherence to guidelines for beta-blocker therapy in heart failure. The design includes site level baseline measurement, feedback, remeasurement after six months, and randomized (by site) comparison samples. The setting is VA sites, with intervention directed at the pharmacy.

Detailed Description

Current evidence-based guidelines in VA recommend one of three beta-blockers (carvedilol, metoprolol succinate, or bisoprolol) that have been shown to reduce mortality in heart failure patients with systolic dysfunction, with recommended target doses. However, Pharmacy Benefits Management (PBM) data indicate that prescribing for beta-blockers in heart failure patients that is not in accordance with guidelines is substantial, both in terms of the agent selected and the dose. Sites will be recruited and randomized to two different intensities of intervention to promote adherence to guidelines.

Registry
clinicaltrials.gov
Start Date
October 2009
End Date
October 2012
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Males and females

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Rate of Adherence to Guideline Prescription

Time Frame: 6 months

full adherence to guideline medication and dose

Secondary Outcomes

  • Progress Toward Adherence to Guideline Prescription(6 months)

Study Sites (1)

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