NCT01556828TerminatedNot Applicable
Analysis of Cutaneous and Hematologic Disorders by High-Throughput Nucleic Acid Sequencing
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Terminated
- Sponsor
- Stanford University
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- Number of mutations
Study Overview
Brief Summary
The goal of this study is to identify genetic changes associated with the initiation, progression, and treatment response of response of cutaneous and hematologic disorders using recently developed high-throughput sequencing technologies. The improved understanding of the genetic changes associated with cutaneous and hematologic disorders may lead to improved diagnostic, prognostic and therapeutic options for these disorders.
Study Design
- Study Type
- Observational
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •18 years of age or older
- •Patient meets the clinical and/or pathologic criteria for the cutaneous or hematologic disorder being examined.
- •Patient is willing to provide skin biopsies and five 10 mL tubes of peripheral blood.
Exclusion Criteria
- •Less than 18 years of age
Outcomes
Primary Outcomes
Number of mutations
Time Frame: 2 years
Identify mutations, changes in DNA copy number, structural rearrangements, or altered coding and non-coding RNA expression
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
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