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The Effect of a Natural Extract on the Post-prandial Blood Glucose Response After Bread Consumption: a Dose-response of Efficacy

Not Applicable
Completed
Conditions
Healthy
Interventions
Dietary Supplement: no added fruit extract
Dietary Supplement: fruit extract
Registration Number
NCT02388503
Lead Sponsor
Unilever R&D
Brief Summary

This study is designed to identify the minimal effective tested dose of fruit extract consumed with a bread which provides a reduction in venous post-prandial blood glucose compared to a reference bread.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
64
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
Referenceno added fruit extractNo added fruit extract
Active 3fruit extractmedium dose of fruit extract
Active 2fruit extractlow dose of fruit extract
Active 4fruit extracthigh dose of fruit extract
Active 1fruit extractlowest dose of fruit extract
Primary Outcome Measures
NameTimeMethod
Positive incremental post-prandial blood glucose area under the curve120 minutes
Secondary Outcome Measures
NameTimeMethod
Post-prandial insulin response180 minutes
AUC of fruit extract calculated by a non-compartmental model180 minutes
Positive incremental post-prandial blood glucose area under the curve180 minutes
AUC of fruit extract calculated by a population model180 minutes

Trial Locations

Locations (1)

Charité research organisation

🇩🇪

Berlin, Charitéplatz 1, Germany

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