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Clinical Trials/NCT03806608
NCT03806608
Active, not recruiting
Not Applicable

Clinical and Radiographic Evaluation of Marginal Bone Changes Around Platform-switching Implants Placed in Crestal or Subcrestal Positions: a Randomized Controlled Clinical Trial

Sun Yat-sen University1 site in 1 country20 target enrollmentApril 17, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Jaw, Edentulous
Sponsor
Sun Yat-sen University
Enrollment
20
Locations
1
Primary Endpoint
Marginal bone loss(MBL)
Status
Active, not recruiting
Last Updated
4 years ago

Overview

Brief Summary

The objective of this randomized controlled trial is to evaluate changes in marginal bone levels and soft tissue dimensions around implants placed with the IAI at different positions in relation to the alveolar crest

Detailed Description

The objective of this randomized controlled trial is to evaluate changes in marginal bone levels and soft tissue dimensions around implants placed with the IAI at different positions in relation to the alveolar crest. Subjects will be included with the absence of 2-4 teeth in the posterior region of the maxilla or mandibular. Twenty patients will be recruited. Two implant placement depths, equicrestal and subcrestal, were randomly assigned to two sites of each patient with a predefined randomization tables (one crestal implant and one subcrestal implant). Patients will be recalled for oral hygiene maintenance and prosthetic controls at 1year, 3 years, 5 years after final restoration.

Registry
clinicaltrials.gov
Start Date
April 17, 2019
End Date
May 2026
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Sun Yat-sen University
Responsible Party
Principal Investigator
Principal Investigator

Baoxin Huang

Principle Investigator

Sun Yat-sen University

Eligibility Criteria

Inclusion Criteria

  • Absence of 2-4 teeth in the posterior region of the maxilla or mandibular;
  • Bone volume sufficient for implants with 4.1-mm size and 8- to 12-mm height and with no need for hard or soft tissue augmentation for implant treatment;
  • Periodontally healthy.

Exclusion Criteria

  • Systemic diseases that may affect bone and soft tissue healing, such as diabetes, osteoporosis, Paget's disease, and patients with cancer;
  • Uncontrolled periodontal disease or poor oral health with neither good nor adequate plaque control;
  • Parafunctional habits, such as the grinding or clenching of teeth;
  • Smoking habit (more than 10 cigarettes per day);
  • Pregnancy and breastfeeding.

Outcomes

Primary Outcomes

Marginal bone loss(MBL)

Time Frame: Change from baseline up to 5 years after implantation

Baseline will be recorded at the time of implantation. Margin bone loss(MBL) will be recorded at 0 day, 4 months, 1 year and 3 years after implant placement.

Secondary Outcomes

  • Plaque index (PI)(Up to 5 years after final restoration)
  • Cumulative survival rate (CSR)(Up to 5 years after final restoration)
  • Pocket probing depth (PPD)(Up to 5 years after final restoration)
  • Bleeding on probing (BOP)(Up to 5 years after final restoration)

Study Sites (1)

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