investigation of the relation between trombo-embolic events and microparticles in essential thrombocythemia and polycythemia vera patients

• Conditions: blood disease; myeloproliferative disorders; 10018865; 10014523

• Registration Number: NL-OMON31395
• Lead Sponsor: Onze Lieve Vrouwe Gasthuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 80

Inclusion Criteria

patients who meet WHO criteria for PV and ET

Exclusion Criteria

we have no exclusion criteria

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Number of Annexin V positive microparticles in patients and controls as well as<br /><br>the expression of different antibodies in this Annexin V positive.<br /><br>Endogene trombine potential of patients and controls.<br /><br>We will describe the relationship of these microparticles with medication,<br /><br>jak2V17 mutation and history of thrombo-embolic events in patients and controls</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>We will describe the relation between these microparticles and Von Willebrand<br /><br>factor antigen and propeptide, E-selectin, thrombocytes, age and gender.</p><br>