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临床试验/IRCT20220607055095N1
IRCT20220607055095N1已完成2 期

Evaluating the effects of the Atomoxetine and Trazodone combination on the number of apneas and apnea-hypopnea sleep index in obstructive sleep apnea patients referred to the sleep clinic of Imam Khomeini hospital.

Tehran University of Medical Sciences0 个研究点目标入组 18 人开始时间: 待定最近更新:
适应症

试验速览

阶段
2 期
状态
已完成
入组人数
18

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 years 至 65 years(—)
性别
All

入选标准

  • Definite diagnosis of obstructive sleep apnea in medical history with AHI>15 in polysomnography
  • lack of compliance treatment with CPAP or BIPAP
  • either the patient is unwilling to have surgery or they are not candidates for surgery in the opinion of the expert

排除标准

  • commodities' existence (excluding controlled blood pressure, hyperlipidemia and diabetes)
  • any underlying cardiac disease, such as arrhythmia that is seen on the ECG
  • History of seizures, Panic disorder, Hyperventilation syndrome, Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
  • Hypersensitivity to lidocaine, atomoxetine or trazodone, substances used in placebo
  • Taking any medication that leads to changes in the physiology of breathing, sleep / wake and muscles Taking any medication that leads to changes in the physiology of breathing, sleeping / waking and muscles
  • Inability to sleep in supine position

研究者

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