IRCT20220607055095N1已完成2 期
Evaluating the effects of the Atomoxetine and Trazodone combination on the number of apneas and apnea-hypopnea sleep index in obstructive sleep apnea patients referred to the sleep clinic of Imam Khomeini hospital.
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 18
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 65 years(—)
- 性别
- All
入选标准
- •Definite diagnosis of obstructive sleep apnea in medical history with AHI>15 in polysomnography
- •lack of compliance treatment with CPAP or BIPAP
- •either the patient is unwilling to have surgery or they are not candidates for surgery in the opinion of the expert
排除标准
- •commodities' existence (excluding controlled blood pressure, hyperlipidemia and diabetes)
- •any underlying cardiac disease, such as arrhythmia that is seen on the ECG
- •History of seizures, Panic disorder, Hyperventilation syndrome, Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
- •Hypersensitivity to lidocaine, atomoxetine or trazodone, substances used in placebo
- •Taking any medication that leads to changes in the physiology of breathing, sleep / wake and muscles Taking any medication that leads to changes in the physiology of breathing, sleeping / waking and muscles
- •Inability to sleep in supine position
研究者
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