Effects of Preoperative Immunonutrition in Patients Undergoing Hepatectomy
Phase 4
Completed
- Conditions
- Bile Duct Cancer
- Interventions
- Dietary Supplement: Oral IMPACT
- Registration Number
- NCT01256047
- Lead Sponsor
- Chiba University
- Brief Summary
The purpose of this study is to determine whether preoperative immunonutrition is effective on infectious complication and Th1/Th2 differentiation in patients with major hepatectomy.
- Detailed Description
The investigators reported that preoperative immunonutrition improve the incidence of postoperative infectious complication in patients after hepatectomy, and modulation of Th1/Th2 differentiation may play important roles in this effect.
Object of this study is to investigate the effects of preoperative immunonutrition on incidence of postoperative infectious complication, and Th1/Th2 balance after hepatectomy.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- hepatectomy
Exclusion Criteria
- age younger than 18 years
- ongoing infection
- gastrointestinal obstruction
- respiratory dysfunction
- cardiac dysfunction
- hepatic dysfunction
- renal failure
- history of recent immunosuppressive or immunological disease
- preoperative evidence of widespread metastatic disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description group A Oral IMPACT preoperative immunonutrition
- Primary Outcome Measures
Name Time Method postoperative infectious complication 30 days
- Secondary Outcome Measures
Name Time Method plasma IL-6, CRP, Th1/Th2 balance 14 days
Trial Locations
- Locations (1)
Chiba University
🇯🇵Chiba, Japan