The ROAD 2.0 to Sustainable Medication Use: Redispensing Unused Oral Anticancer Drugs

Not Applicable

Recruiting

• Conditions: Pharmacy; Oncology; Cancer; Drug Prescriptions
• Interventions: Other: redispensing oral anticancer drugs

• Registration Number: NCT06566560
• Lead Sponsor: Radboud University Medical Center

Brief Summary

The goal of this prospective intervention study is to investigate the effectiveness of redispensing unused oral anticancer drugs.

The main questions it aims to answer are:

* What are the cost-savings of redispensing unused oral anticancer drugs?

* What is the environmental impact of redispensing unused oral anticancer drugs?

Researchers will compare redispensing unused oral anticancer drugs to the standard practice of disposal.

Participants will receive their oral anticancer drugs in a sealed bag with a temperature indicator if needed. They will be asked to return any unused oral anticancer drugs to the pharmacy during their next visit to the hospital.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-01-10
• Status Verified: 2024-08
• Study First Submitted: 2024-08-06
• Study First Submitted QC: 2024-08-20
• Last Update Submitted: 2024-08-20
• Study First Posted: 2024-08-22
• Last Update Posted: 2024-08-22
• Primary Completion: 2024-12-31
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 2500

Inclusion Criteria

• Patients of all ages
• A clinical diagnosis of cancer using an oral anticancer drug that requires storage at room temperature according to the Summary of Product Characteristics (SmPC).

Exclusion Criteria

• Patients that do not understand the Dutch or English language, in written or spoken.
• Patients receiving prescriptions that contain an amount of tablets that deviates from the regular package size, resulting in the pharmacy dispensing an opened package

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Intervention	redispensing oral anticancer drugs	-

Primary Outcome Measures

Name	Time	Method
The environmental impact of redispensing unused oral anticancer drugs of verified quality compared to standard practice of disposal.	From date of first dispensing unit the date of last unused medication package returning to the pharmacy, assessed up to 16 months	Environmental impact will be measured in CO2-eq
Cost-savings obtained by redispensing unused oral anticancer drugs of verified quality compared to standard practice of disposal.	From date of first dispensing unit the date of last unused medication package returning to the pharmacy, assessed up to 16 months.	Cost savings will be measured in euros

Secondary Outcome Measures

Name	Time	Method
Patients' reasons for not wanting to participate in a redispensing program for oral anticancer drugs.	From date of first invitation to participate in the study until the end of the recruitment period, up to 8 months.
The proportion of usability of returned medication for redispensing and the reasons for quality disapproval.	From date of first dispensing unit the date of last unused medication package returning to the pharmacy, assessed up to 16 months
The proportion of returned unused oral anticancer drugs and reasons thereof.	From date of first dispensing unit the date of last unused medication package returning to the pharmacy, assessed up to 16 months

Trial Locations

Locations (1)

Radboudumc; 🇳🇱 Nijmegen, Gelderland, Netherlands