Study of the effect of Low-Level Light Therapy on the salivary glands, proteomic analysis, quality of life and psychological aspects of individuals with Sjögren's Syndrome

Not Applicable

Recruiting

• Conditions: Quality of Life; Salivary Proteins and Peptides; Depression; Anxiety; Stress, Psychological; C05.550.114.154.774

• Registration Number: RBR-10rskkf5
• Lead Sponsor: Faculdade de Odontologia de Bauru, Universidade de São Paulo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2024-01-07
• Last Update Posted: 23 January 2024
• Study Completion: 2025-12-01

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Individuals receiving dental treatment at the FOB-USP Stomatology clinic who complain of dry mouth not explained by disorders other than Sjogren's Syndrome, with any amount of unstimulated and stimulated salivary flow, over 18 years of age.

Exclusion Criteria

Individuals with dry mouth who have undergone head and neck irradiation or other disorders not associated with Sjogren's Syndrome and individuals currently taking secretagogues.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The results are expected to show a partial increase in salivary flow and an improvement in the complaint of xerostomia (dry mouth symptom) in patients with Sjogren's Syndrome.

Secondary Outcome Measures

Name	Time	Method
It is also hoped that the results will show a positive impact of oral health on quality of life and that the psychological condition of these individuals will improve significantly.;We hope to demonstrate markers in salivary proteins that will help us to understand and establish a reliable therapeutic proposal after Low-Level Light Therapy applications in the the major and minor salivary glands of patients with Sjogren's Syndrome.