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临床试验/NCT04514055
NCT04514055已完成不适用

Evaluation of a De-epithelialized Free Gingival Connective Tissue Graft Wall Technique in Management of Cairo's RT2 and RT3 With Intra-bony Defects: A Case Series

Cairo University1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2020年10月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
10
试验地点
1
主要终点
Gingival recession depth

研究概览

简要总结

Recession presents a day to day challenge due to the high esthetic demand of the patients. The prevalence, extent, and severity of recession associated with intra-bony defects due to periodontitis increases with age rendering the success of the root coverage procedures questionable due to loss of interdental papillary support. .

Therefore, connective tissue graft wall technique in cases of Cairo's RT2 and RT3 gingival recession associated with intra bony defects seems promising with regard to recession depth reduction and radiographic bone fill.

详细描述

Recession is usually treated by an array of mucogingival surgical techniques. The choice of the procedure depends on the morphology of the recession defect. Full root coverage in RT2 and RT3 gingival recession defects cannot always be predictably achieved due to the presence of bone loss. Improvement is further complicated when these recessions are associated with intra-bony defects as mucogingival surgical techniques are not designed to treat intra-bony defects. The preferred surgical modality for treatment of intrabony defects is guided tissue regeneration. However when considering recession defects, the amount of root coverage achieved by GTR may be limited with less results achieved.

Most of the root coverage procedures have proven to be successful, however, when recession is associated with intrabony defect especially in cases of low height and thickness of keratinized tissue and GTR is performed, the treatment results were unpredictable and it was found that the recession might increase post-surgically, so the procedure might offer a limited benefit.

Therefore, the technique introduced by Zucchelli et al. in 2014 in cases of RT2 and RT3 gingival recession associated with intra bony defects seems promising with regard to recession depth reduction and radiographic bone fill. A simplified papilla preservation technique was performed on the defect site, a de-epithelialized free gingival graft was used to treat the gingival recession present and intrabony defects because it acted as a membrane, creating a buccal wall to the intra-bony defect from one side and on the palatal aspect since no flap elevation was done. The palatal connective tissue acted as a palatal wall preventing gingival epithelium and connective tissue from contacting the space created allowing both improved root coverage and bone fill. He reported interproximal probing depth reduction, clinical attachment gain, improvement in the papilla covering the intrabony defect regarding the gingival thickness and root coverage and complete bone fill was shown radiographically in 1 year.

This technique needs more investigations, but it seems encouraging to improve regenerative and esthetic parameters in the treatment of deep infrabony defects, in one surgical session.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
20 Years 至 60 Years(Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Teeth with buccal RT2 and RT3 recession associated with an intra-bony defect on single rooted teeth.
  • •Single and multiple recessions.
  • •Full mouth plaque score (FMPS )<20% at baseline.
  • •Full mouth bleeding score (FMBS )<10% at baseline.
  • •Systemically healthy.
  • •Cooperative patients.

排除标准

  • •Pregnancy and lactation.
  • •Stage 4 Grade C periodontitis.

研究组 & 干预措施

De-epithelialized connective tissue graft wall

Experimental

Simplified papilla preservation flap will be applied in the narrow interproximal spaces (≤2 mm), where an oblique incision starting from the gingival margin at the buccal-line angle of the involved tooth reaching the mid-interproximal portion of the papilla under the contact point of the adjacent tooth will be performed using a 15c blade.

A free gingival graft will be obtained from the hard palate and de-epithelized extra-orally.

A Coronally advanced flap will be performed. The de-epithelialized FGG will be sutured coronally using a 6-0 vicryl suture to the anatomical papillae of the two teeth adjacent to the defect and apically to the periosteum left in place apical to the exposed bone.

The flap will be sutured using internal Horizontal mattress suture at the base of the simplified papilla and a vertical mattress suture will be placed in a more coronal position so complete soft tissue closure can be obtained.

干预措施: De-epithelialized connective tissue graft wall (Procedure)

结局指标

主要结局

Gingival recession depth

时间窗: Changes at 3 and 6 months post-operative

Measured from the cementoenamel junction to the gingival margin using a William's graduated periodontal probe. The probe will be inserted into the sulcus gently parallel to the long axis of the tooth.

次要结局

  • Bleeding on Probing(At 6 months post-operative)
  • Radiographic bone fill(At 6 months post-operative)
  • Percentage of Root Coverage(Changes at 3 and 6 months post-operative)
  • Probing Depth(Changes at 3 and 6 months post-operative)
  • Width of the Keratinized Tissue(At 3 and 6 months post-operative)
  • Gingival Recession Width(Changes at 3 and 6 months post-operative)
  • Post-Operative Pain(At 7 and 14 days post-operative)
  • Plaque Index(At 6 months post-operative)
  • Gingival Thickness(Changes at 3 and 6 months post-operative)
  • Clinical Attachment Level(At 3 and 6 months post-operative)
  • Post-Operative patient's Satisfaction(At 6 months post-operative)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mariam Galal Bendary

principal investigator

Cairo University

研究点 (1)

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