Effects of Total and Selective Caries Removal - Requiring or Avoiding Vital Pulp Therapy - on Pulp Vitality and Postoperative Pain in Deep Carious Mature Permanent Teeth: A Split-Mouth Clinical Study

Not Applicable

Not yet recruiting

• Conditions: Pulp Exposure, Dental; Deep Dental Caries

• Registration Number: NCT07041905
• Lead Sponsor: Cukurova University

Brief Summary

The effect of selective caries cleaning and total caries cleaning on pulp health and post operative pain in teeth with deep caries will be investigated.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-06
• Study First Submitted: 2025-06-19
• Study First Submitted QC: 2025-06-19
• Study First Posted: 2025-06-27
• Last Update Submitted: 2025-06-30
• Last Update Posted: 2025-07-03
• Study Start: 2025-07-04
• Primary Completion: 2025-10-17
• Study Completion: 2026-03-06

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• Patients aged ≥15 years with bilateral deep carious mature permanent teeth.
• Positive vitality test (cold sensitivity).
• No spontaneous pain or periapical radiolucency.
• Willingness to attend 6- and 12-month follow-ups

Exclusion Criteria

• Uncontrolled systemic diseases Pregnancy or allergy to dental materials used Teeth with irreversible pulpitis (spontaneous pain, necrosis) Non-restorable teeth (fractures, extensive decay)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
pulp survival at twelve months	twelve months	The pulp is expected to remain vital, with no percussion tenderness and no spontaneous pain
Early postoperative pain intensity (VAS) after total vs. selective excavation	first week	The patient will be asked to rate his/her pain on day 1, 3 and 7 according to VAS
dentin bridge formation	twelve months	no dentin bridge formation is expected in selective caries cleaning, while dentin bridge formation will be observed radiologically in total cleaning