The Comparative Results of Penicillin Testing in Patients With History of Allergic Reactions to Betalactams Between Using In-house Penicillin Test Preparation and Commercial Available Penicillin Testing Kit
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 63
- 试验地点
- 1
- 主要终点
- The skin testing results of in-house penicillin skin test and Penicillin G Sodium compared to commercial penicillin testing kit
研究概览
简要总结
This study aims to compare the readings of skin testing results in patients with suspected penicillin allergy between in-house penicillin test preparation and commercial available penicillin testing kit.
详细描述
The results of skin test with immediate reading will be compared between alkali-treated penicillin G and DAP reagents from Diater
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 15 Years 至 65 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with history of hypersensitivity reactions to betalactams; penicillin, aminopenicillins, and cephalosporins
- •15-65 years of age
排除标准
- •On antihistamine/ cannot discontinue antihistamine before the test
- •Having asthma exacerbation
- •Being pregnant
- •Suffering from severe systemic disease/ in bad health
研究组 & 干预措施
In-house penicillin testing preparation
In-house penicillin testing prepared from alkali-treated penicillin G
干预措施: Immediate skin test (Procedure)
Commercial penicillin test kit
Commercial penicillin test kit order from Diater company
干预措施: Immediate skin test (Procedure)
Penicillin G Sodium
Penicillin G Sodium from routine clinical use
干预措施: Immediate skin test (Procedure)
结局指标
主要结局
The skin testing results of in-house penicillin skin test and Penicillin G Sodium compared to commercial penicillin testing kit
时间窗: 1 year
次要结局
- Clinical correlation and side effects(1 year)
- Correlations between Penicillin skin test result with specific IgE and/or basophil activation test(1 year)