JPRN-jRCTs011180023已完成未知
Development of photodynamic diagnostic method using aminolevulinic acid (5-ALA) against thoracic malignant tumors - PDTMT
Kitada Masahiro0 个研究点目标入组 267 人开始时间: 2019年3月19日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 267
研究概览
简要总结
We have developed an optical diagnostic method for pleural malignant lesions in combination with 5ALA, which is a photosensitive substance, and autofluorescence. As a result, localization diagnosis of lesions was possible, and pleural invasion factor could be diagnosed with sensitivity of 90.3% in the case of lung adenocarcinoma. It may contribute as a diagnostic method that complements conventional diagnostic imaging and visual diagnosis.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 <= 80age old（—）
- 性别
- All
入选标准
- •1.Patients with chest malignancy (lung cancer, metastatic lung tumor, malignant breast tumor, thoracic lymph node metastasis from breast cancer) .
- •2.Surgical samples with diagnosis of chest malignancy on image or pathological diagnosis.
- •3.Cases requiring diagnosis by thoracoscopic biopsy including lymph nodes.
- •4.After receiving sufficient explanation about this exam, after understanding the sufficient understanding, cases where document agreement was acquired with the free will of the patient himself / herself.
排除标准
- •1. Cases of pregnancy or lactation.
- •2. Patients with porphyria.
- •3. Drugs that are known to cause photosensitivity: tetracycline antibiotics, sulfonamide type preparations, new quinolone type antibacterial agents, hypericin (Hypericum perforatum extract), etc. St. John's Wort patients who are receiving food containing.
- •4. Cases with chronic hepatitis, chronic renalfailure.
- •5. Cases in which the result of treatment of malignant tumor does not change by this procedure.
研究者
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