Discontinuation of aspirin as primary prevention and cardiovascular events in diabetes
Completed
- Conditions
- Diabetic patient at risk of atherosclerotic cardiovascular diseaseAspirin discontinuationDiabetes mellitusprimary prevention
- Registration Number
- TCTR20220114002
- Lead Sponsor
- /A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 298
Inclusion Criteria
Thai male and female residents with 45 years of age will be conducted in Khon Kaen Hospital
Exclusion Criteria
1. All patients with diagnostic records of prior cardiovascular events
2. Current antithrombotic users
3. Patients whose domicile are not in Muang district of Khon Kaen province will also be excluded due to lack of accessible medication history, p
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Aspirin discontinuation Up to 3 years before the index date Discontinuation of aspirin or lost to follow-up after usage of aspirin as primary prevention
- Secondary Outcome Measures
Name Time Method Aspirin non-adherence Up to 3 years before the index date Patients with history of aspirin prescription with lower than 80% medication possession ratio within the recorded period measured using rates of prescription refill method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
How does aspirin discontinuation impact COX-2 inhibition and inflammation in diabetes-related cardiovascular risk?
What are the comparative outcomes of aspirin discontinuation vs. standard antiplatelet therapy in diabetes primary prevention?
Which biomarkers predict cardiovascular risk after aspirin cessation in diabetic patients?
What are the risks of aspirin discontinuation in diabetes for ASCVD events and how are they managed?
Are there alternative antiplatelet strategies to aspirin for diabetes patients with ASCVD risk?