Determination of Dominant Pain Phenotype in Patients With Carpal Tunnel Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 113
- 试验地点
- 1
- 主要终点
- Numerical Rating Scale
研究概览
简要总结
The aim of this study was to determine the dominant pain phenotype in a group of patients with Carpal Tunnel Syndrome by applying the International Association for the Study of Pain (IASP) criteria.
详细描述
Voluntary participants between the ages of 18-65 who have been diagnosed with CTS will be included in the study.The 7 steps in the Clinical Criteria/Rating System determined by the International Association for the Study of Pain (IASP) for Nosiplastic Pain and Carpal Tunnel Syndrome will be applied to people with CTS. Thermal pain threshold, mechanical pain sensitivity and static/dynamic allodynia will be evaluated to determine pain hypersensitivity (Step 5). Specific questions will be asked to confirm the history of hypersensitivity in patients (Step 6). Finally, comorbidities, if any, will be determined (Step 7). As a result, the pain phenotype of patients with CTS will be determined (Nociceptive, Neuropathic or Nosiplastic). Shapiro-Wilk test will be performed to determine the distribution of the data. One-way ANOVA (continuous) or Kruskal-Wallis (categorical) will be used to examine whether the dependent variables differ between groups. For significant F-test, an additional investigation of differences between groups will be performed with Gabriel's post hoc procedure.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Being diagnosed with CTS
- •Being between the ages of 18-65
- •Volunteering to participate in the study
排除标准
- •Having systemic inflammatory disease
- •Having a disease that may cause polyneuropathy such as diabetes mellitus
- •Having a pacemaker
- •Having a disease affecting the central nervous system
- •Having cervical radiculopathy
- •History of previous operation or local steroid injection due to CTS
- •Hypersensitivity to heat and cold
结局指标
主要结局
Numerical Rating Scale
时间窗: 1 minute
Patients rate the current pain intensity from 0 ("no pain") to 10 ("worst possible pain").
次要结局
- Cold Pain Threshold(2 minutes)
- Hot Pain Threshold(2 minutes)
- Mechanical Pain Threshold(3 minutes)
- Static mechanical allodynia(3 minutes)
- Dynamic Mechanical Allodynia(3 minutes)
研究者
Emrah Afsar
Phd
Kutahya Health Sciences University
