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临床试验/NCT06635200
NCT06635200已完成不适用

Determination of Dominant Pain Phenotype in Patients With Carpal Tunnel Syndrome

Kutahya Health Sciences University1 个研究点 分布在 1 个国家目标入组 113 人开始时间: 2024年11月5日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
113
试验地点
1
主要终点
Numerical Rating Scale

研究概览

简要总结

The aim of this study was to determine the dominant pain phenotype in a group of patients with Carpal Tunnel Syndrome by applying the International Association for the Study of Pain (IASP) criteria.

详细描述

Voluntary participants between the ages of 18-65 who have been diagnosed with CTS will be included in the study.The 7 steps in the Clinical Criteria/Rating System determined by the International Association for the Study of Pain (IASP) for Nosiplastic Pain and Carpal Tunnel Syndrome will be applied to people with CTS. Thermal pain threshold, mechanical pain sensitivity and static/dynamic allodynia will be evaluated to determine pain hypersensitivity (Step 5). Specific questions will be asked to confirm the history of hypersensitivity in patients (Step 6). Finally, comorbidities, if any, will be determined (Step 7). As a result, the pain phenotype of patients with CTS will be determined (Nociceptive, Neuropathic or Nosiplastic). Shapiro-Wilk test will be performed to determine the distribution of the data. One-way ANOVA (continuous) or Kruskal-Wallis (categorical) will be used to examine whether the dependent variables differ between groups. For significant F-test, an additional investigation of differences between groups will be performed with Gabriel's post hoc procedure.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Being diagnosed with CTS
  • Being between the ages of 18-65
  • Volunteering to participate in the study

排除标准

  • Having systemic inflammatory disease
  • Having a disease that may cause polyneuropathy such as diabetes mellitus
  • Having a pacemaker
  • Having a disease affecting the central nervous system
  • Having cervical radiculopathy
  • History of previous operation or local steroid injection due to CTS
  • Hypersensitivity to heat and cold

结局指标

主要结局

Numerical Rating Scale

时间窗: 1 minute

Patients rate the current pain intensity from 0 ("no pain") to 10 ("worst possible pain").

次要结局

  • Cold Pain Threshold(2 minutes)
  • Hot Pain Threshold(2 minutes)
  • Mechanical Pain Threshold(3 minutes)
  • Static mechanical allodynia(3 minutes)
  • Dynamic Mechanical Allodynia(3 minutes)

研究者

发起方
Kutahya Health Sciences University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Emrah Afsar

Phd

Kutahya Health Sciences University

研究点 (1)

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