Upper Limb Function and Visuospatial Exploration After Stroke

Completed

• Conditions: Stroke
• Interventions: Other: No intervention

• Registration Number: NCT03135093
• Lead Sponsor: University of Zurich

Brief Summary

This project is a cross-sectional, observational mono-center study with prospective data collecting.

This study aims to further explore quality of upper limb movement in relation to characteristics of visuospatial exploration in stroke subjects and healthy subjects by a applying comprehensive measurements of clinical scales and kinematic data in capacity- and performance-based activities. The results will contribute to assessing and monitoring quality of upper limb movements and visuospatial attention and their relationship.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-04-01
• Study First Submitted: 2017-04-26
• Study First Submitted QC: 2017-04-26
• Study First Posted: 2017-05-01
• Primary Completion: 2019-12-30
• Study Completion: 2019-12-30
• Status Verified: 2020-01
• Last Update Submitted: 2020-02-06
• Last Update Posted: 2020-02-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

• Subjects of 18 years and older with chronic ischemic stroke (> 6 month) restricted to one hemisphere (confirmed by CT/MRI)
• With impairments in upper limb function and at least partial ability to lift the arm against gravity, flex and extend the fingers
• Without relevant pre-existing limitations in arm and hand function (orthopaedic, muscular, neurologic)
• Written informed consent after participants's information

Exclusion Criteria

• Increased muscle tone in the upper limb with limited rang of motion
• Severe sensory deficits in the upper limb
• Clinically significant concomitant disease (affecting the upper limb or impaired vision, e.g. due to glaucoma etc.)
• Contraindications on ethical grounds (vulnerable persons)
• Known or suspected non-compliance, drug or alcohol abuse
• Severe communication or cognitive deficits, that cause inability to follow the procedures

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Stroke subjects	No intervention	-
Healthy subjects	No intervention	-

Primary Outcome Measures

Name	Time	Method
Upper limb movement quality	One day	Fugl-Meyer Assessment of the upper extremity (FMA-UE), kinematic data (e.g. joint angles, hand workspace)
Visuospatial exploration	One day	Eye-tracking data (e.g. area of interest, eye movements: saccades, fixations) and to rule out stroke-related deficits of visuospatial attention, clinical tests

Trial Locations

Locations (1)

cereneo Schweiz AG; 🇨🇭 Vitznau, Luzern, Switzerland