The Investigation of the Depression in Osteoarthritis

• Conditions: Depression
• Interventions: Other: There is no intervention.

• Registration Number: NCT02924662
• Lead Sponsor: Dalian Municipal Central Hospital

Brief Summary

Studies have reported that the patient's psychological state such as anxiety, depression and other emotion affect the therapeutic effect of osteoarthritis, also may be the important reason for the poor knee joint osteoarthritis efficacy.

The aim of this study are firstly to investigate the depression status of patients with osteoarthritis. Secondly, the study will aim to assess whether osteoarthritis progression will affect depression status, ultimately, provide reference for clinical.

Detailed Description

Not available

Study Timeline

• Status Verified: 2016-10
• Study Start: 2016-10
• Study First Submitted: 2016-10-04
• Study First Submitted QC: 2016-10-04
• Last Update Submitted: 2016-10-04
• Study First Posted: 2016-10-05
• Last Update Posted: 2016-10-05
• Primary Completion: 2017-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Meet the 1986 American College of Rheumatology (ACR) clinical criteria for knee osteoarthritis and the 2010 Chinese Medical Association clinical criteria for knee osteoarthritis.

Exclusion Criteria

Patients with rheumatoid arthritis patients with a history of depression before osteoarthritis pathogenesis patients who can't cooperate with related inspection and assessment Patients with mental illness

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Kellgren and Lawrence classification I	There is no intervention.	Grade I Kellgren and Lawrence radiographic changes.

Primary Outcome Measures

Name	Time	Method
Western Ontario and McMaster OA index (WOMAC)	Day 1
American knee society knee score	Day 1
Hamilton Depression Scale-17（HAMD-17）	Day 1