Comparison of efficacy of low vs. high dose of Atorvastatin and Rosuvastatin in reducing hs-CRP and IL-6 in diabetic patient referred to the Institute of Endocrinology and Metabolism
Phase 2
Recruiting
- Conditions
- Efficacy of low dose and high dose Atorvastatin and Rusovastatin in Diabetic patients.
- Registration Number
- IRCT20180929041169N2
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Diabetic patients who need to receive Statin according to ADA 2018
Exclusion Criteria
Pregnancy
Patient with Genetic Disease
Use of other lowering agent other than Statin
Hx of Angina
Hx of Nephropathy
Hx of Hypothyroidism
Hx of liver Disease or ALT> 3 ULN,AST>3 ULN
CPK> 10 ULN
Patients on Corticosteroids
Patients with Cyclosporins or Hormone replacement therapy
Hx of use of Alcohol
Acute and chronic infectious or Inflammatory disease
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measurement of highly sensitive C reactive protein & Interleukin-6. Timepoint: At the initial and 2 month after medication used. Method of measurement: Blood sampling with Elisa assay.
- Secondary Outcome Measures
Name Time Method