跳至主要内容
临床试验/NCT01690715
NCT01690715终止不适用

Prognostic Value Related to the Presence of Thrombosis or Portal Vein Invasion in Patients With Hepatocellular Carcinoma Submitted to Surgery

Hospital Sirio-Libanes1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2012年7月最近更新:
适应症

试验速览

阶段
不适用
状态
终止
发起方
入组人数
50
试验地点
1
主要终点
Prognosis (disease graduation)

研究概览

简要总结

A retrospective study based on analysis of medical records of patients with hepatocellular carcinoma treated at the Hospital Sírio-Libanês (Sao Paulo-Brazil) between 2001 and 2011 with diagnosis confirmed by imaging or histological specimen underwent surgical resection with curative intent. The study aims to determine the prognostic value of vascular complications related to cancer and to evaluate the survival rate of these patients, comparing the data with those reported in the literature.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者
否

入选标准

  • •hepatocellular carcinoma confirmed by imaging or histological specimen underwent surgical resection, with or without hepatic cirrhosis association;
  • •presence of venous outflow obstruction, either by direct tumor invasion or thrombosis, on portal vein or one of its main vessels;

排除标准

  • •Patients undergoing prior systemic treatment;
  • •Patients presenting incomplete data that do not allow their classification according to the stratification models;
  • •Patients whose information of progression or death can not be recovered;

结局指标

主要结局

Prognosis (disease graduation)

时间窗: 1 to 3 years

The carcinoma prognosis in the presence of vascular complications related to cancer, characterized by invasion or portal vein thrombosis.

次要结局

  • Relation established between survival and degree of underlying liver dysfunction(1 to 3 years)
  • Survival rate in years(1 to 3 years)

研究者

发起方
Hospital Sirio-Libanes
申办方类型
Other
责任方
Principal Investigator
主要研究者

Frederico Perego Costa

Attending physician

Hospital Sirio-Libanes

研究点 (1)

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