Paracetamol Plus Morphine in ED
Overview
- Phase
- Phase 4
- Intervention
- Paracetamol+Morphine
- Conditions
- Renal Colic
- Sponsor
- Akdeniz University
- Enrollment
- 136
- Primary Endpoint
- pain reductions in VAS scores during the 60th and 90th minutes
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
This randomized, placebo-controlled trial evaluated the analgesic efficacy and safety of intravenous morphine-paracetamol combination and morphine-dexketoprofen combination morphine for the optimum treatment of renal colic. Combination of IV morphine and paracetamol is as effective and rapid as combination of IV Morphine and IV dexketoprophen for optimum treating of renal colic.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Renal colic patients -
Exclusion Criteria
- •Not renal colic patients
Arms & Interventions
Placebo
Intervention: Paracetamol+Morphine
Placebo
Intervention: Dexketoprofen plus Morphine
Placebo
Intervention: Placebo plus Morphine
Paracetamol
Intervention: Paracetamol+Morphine
Paracetamol
Intervention: Dexketoprofen plus Morphine
Paracetamol
Intervention: Placebo plus Morphine
Dexketoprofene
Intervention: Paracetamol+Morphine
Dexketoprofene
Intervention: Dexketoprofen plus Morphine
Dexketoprofene
Intervention: Placebo plus Morphine
Outcomes
Primary Outcomes
pain reductions in VAS scores during the 60th and 90th minutes
Time Frame: 60 minutes
Secondary Outcomes
- Need for rescue analgesic(30 minutes)