Transcranial Direct Current Stimulation Aided Rehabilitation of Gait in Subacute Stroke
Not Applicable
Terminated
- Conditions
- StrokeNeurorehabilitation
- Registration Number
- NCT01927458
- Lead Sponsor
- University of Aarhus
- Brief Summary
The purpose of this study is to determine if transcranial direct current stimulation (tDCS)applied over the lower extremity motor cortex in conjunction with treadmill training is effective for improving gait in patients with subacute stroke and to evaluate the effect and predictive value of a single session of anodal tDCS.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 6
Inclusion Criteria
- Age ≥ 18 years
- Onset of stroke less than 14 days
- First ischemic stroke causing lower limb weakness (MRC score ≤4 in knee extensors) and gait impairment
Exclusion Criteria
- Contraindications to MRI or TMS
- Other neurological disorders
- Significant somatic or psychiatric disorders
- History of seizures
- Language or cognitive disorders prohibiting participation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Maximal gait speed using the 10-m walking test Baseline and follow up immediately following the 4 weeks intervention
- Secondary Outcome Measures
Name Time Method Changes in cortical excitability measures Baseline We will measure cortical excitability using single pulse transcranial magnetic stimulation (TMS) before and after 1st stimulation session. We will compare the measurements from before stimulation to after stimulation.
Dynamometry: the maximal isometric force of muscles will be assessed by Biodex System 3 PRO dynamometer Baseline and immediately following the 4 weeks intervention
Trial Locations
- Locations (1)
Hammel Neurocenter
🇩🇰Hammel, Denmark
Hammel Neurocenter🇩🇰Hammel, Denmark