Transcranial Direct Current Stimulation Aided Rehabilitation of Gait in Subacute Stroke

University of Aarhus1 site in 1 country6 target enrollmentMarch 2013

ConditionsStroke Neurorehabilitation

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Stroke
Sponsor: University of Aarhus
Enrollment: 6
Locations: 1
Primary Endpoint: Maximal gait speed using the 10-m walking test
Status: Terminated
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to determine if transcranial direct current stimulation (tDCS)applied over the lower extremity motor cortex in conjunction with treadmill training is effective for improving gait in patients with subacute stroke and to evaluate the effect and predictive value of a single session of anodal tDCS.

Registry

clinicaltrials.gov

Start Date

March 2013

End Date

December 2015

Last Updated

9 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

University of Aarhus

Responsible Party

Principal Investigator

Krystian Figlewski

University of Aarhus

Eligibility Criteria

Inclusion Criteria

•Age ≥ 18 years
•Onset of stroke less than 14 days
•First ischemic stroke causing lower limb weakness (MRC score ≤4 in knee extensors) and gait impairment

Exclusion Criteria

•Contraindications to MRI or TMS
•Other neurological disorders
•Significant somatic or psychiatric disorders
•History of seizures
•Language or cognitive disorders prohibiting participation

Outcomes

Primary Outcomes

Maximal gait speed using the 10-m walking test

Time Frame: Baseline and follow up immediately following the 4 weeks intervention

Secondary Outcomes

Changes in cortical excitability measures(Baseline)
Dynamometry: the maximal isometric force of muscles will be assessed by Biodex System 3 PRO dynamometer(Baseline and immediately following the 4 weeks intervention)