Stress reactivity in psychosis: the association between traumatic events, genetic vulnerability and psychotic reactivity to stress
Recruiting
- Conditions
- psychosisschizophrenia10039628
- Registration Number
- NL-OMON39714
- Lead Sponsor
- niversiteit Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
1) aged between 18-60
2) sufficient command of the Dutch language
3) no intellectual impairment (IQ>80)
4) Additional inclusion criteria for the 22q11DS group:
A confirmed deletion at chromosome 22q11
Exclusion Criteria
1) Current use of psychotropic medication (non-patients only)
2) Current cannabis dependence
3) Current alcohol dependence
5) Severe endocrine, cardiovascular or brain disease
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Psychotic experiences as measured in daily life (PsyMate)<br /><br>Stress as measured in daily life (PsyMate)</p><br>
- Secondary Outcome Measures
Name Time Method <p>Cortisol niveaus as measured in daily life (saliva samples)<br /><br>The amount of experienced traumatic events as measured by questionnaires and<br /><br>interviews<br /><br>Genetic risk for psychosis (DNA)</p><br>