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Clinical Trials/NCT07352319
NCT07352319
Completed
Not Applicable

Effects of Lower Body Plyometric Training on Serum CPK and Creatinine Levels in Collegiate Female Volleyball Players: An Experimental Study

Cairo University0 sites60 target enrollmentStarted: January 12, 2022Last updated:

Overview

Phase
Not Applicable
Status
Completed
Enrollment
60

Overview

Brief Summary

Eight-week interventional study to evaluate whether lower-body plyometric training alters serum creatine phosphokinase (CPK) and creatinine levels in female collegiate volleyball players. Sixty participants were randomized to experimental (plyometrics twice weekly) or control (routine volleyball) groups. Blood sampling occurred at baseline; days 2, 4, and 6; and weeks 1, 2, 4, 6, and 8.

Detailed Description

Intervention adapted from James & Robert (2015). Experimental group completed progressive lower-body plyometrics twice weekly (Monday/Wednesday) over eight weeks with warm-up and cool-down. Exercises included squat jump; jump to box (30 cm); tuck jump; split squat jump; lateral hurdle jump (50 cm); zigzag jump; single-leg tuck jump; and depth jump (80 cm). Control group continued routine volleyball activities and did not perform low/medium/high-intensity plyometrics. Primary biomarker (serum CPK) assessed via CK-NAC optimized IFCC method; serum creatinine by modified Jaffe's method. Two-way ANOVA with Bonferroni post hoc used. Findings: CPK increased from day 2, peaked day 4, stabilized to week 2, then declined toward baseline by week 8; creatinine remained stable.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Prevention
Masking
None

Eligibility Criteria

Ages
18 Years to 25 Years (Adult)
Sex
Female
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Active collegiate female volleyball players
  • consent to participate
  • no prior plyometric training program.

Exclusion Criteria

  • Neuromuscular impairments
  • recent injuries.

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Mariam Elsayed Mohamed Abd Alaal

Professor

Cairo University

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