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MA-ASAP at Independent Abortion Clinics: A Demonstration Project

Not Applicable
Completed
Conditions
Abortion Early
Interventions
Other: Screening for Eligibility
Registration Number
NCT05781061
Lead Sponsor
Gynuity Health Projects
Brief Summary

In this study, the investigators propose to conduct a parallel study to MA-ASAP (ClinicalTrials.gov Identifier: NCT05278780) at an independent clinic.

Detailed Description

In this study, the investigators propose to conduct a parallel study to the MA-ASAP pilot study (ClinicalTrials.gov Identifier: NCT05278780) at one or more independent abortion clinics. This new study will be similar in structure to pilot study, except that all completed screening questionnaires will be sent to the study site rather than only those deemed eligible according a computer algorithm. The investigators expect that this change will better serve the needs of both clinics and patients, and it will also allow us to assess whether the algorithm is overly restrictive, i.e., whether it is excluding patients who are in fact eligible for MA. The primary goal of the study is to collect data on feasibility of the approach and safety. Secondarily, the investigators aim to assess the ability of a defined set of responses to the screening questionnaire to predict the clinician's decision about whether a clinical consultation is needed.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
50
Inclusion Criteria
  • Can speak and read English
  • Has an address in a state where the study clinicians are licensed to practice medicine and where the service is legal
  • Is old enough to consent to abortion and study participation without parental consent in the study state
  • Has reviewed the study website
  • Has had a positive pregnancy test
  • Has signed the study informed consent form (ICF), which will be included within the questionnaire
  • Is pregnant with a gestational age of ≤77 days from last menstrual period
  • Desires MA
  • Has no symptoms of or risk factors for ectopic pregnancy
  • Has no medical contraindications to MA, specifically:

Hemorrhagic disorder or concurrent anticoagulant therapy Chronic adrenal failure Concurrent long-term systemic corticosteroid therapy Inherited porphyria Allergy to mifepristone or misoprostol, or other prostaglandin

  • Is not asked by the site to have a synchronous consultation with clinician OR facility-based tests such as ultrasound, laboratory tests, examination, etc.
  • Is comfortable obtaining the abortion pills without a pre-treatment ultrasound and without speaking by phone or video with the abortion provider.
Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Asynchronous ScreeningScreening for EligibilityParticipants will be screened for medication abortion eligibility using written or online materials and questionnaires, without a synchronous conversation between the prescribing clinician and the patient.
Primary Outcome Measures
NameTimeMethod
Proportion of participants that are followed through the study6 months

The numbers and proportions of people who complete the questionnaire once initiated, are reached by study staff after submitting a completed questionnaire, and are ultimately followed through the study.

Study site satisfaction (self-reported)6 months

Interest on the part of study sites to continue to utilize this approach to MA provision after the study ends.

Incidence of Treatment-Emergent Adverse Events6 months

Proportion of treated participants with SAE related to the study

Incidence of participant questions6 months

The proportion of participants who have questions after completing the questionnaire and the types of questions that are asked.

Incidence of reported problems by site staff6 months

Problems with the study process as reported by site staff

Secondary Outcome Measures
NameTimeMethod
Efficacy of computer algorithm to determine MA eligibility6 months

We will estimate the predictive value of this algorithm for selecting participants who were deemed eligible for MA or ultimately did receive treatment without a synchronous consultation or facility-based tests

Trial Locations

Locations (1)

All Families Healthcare

🇺🇸

Whitefish, Montana, United States

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