Effect of Intermittent Theta Burst Stimulation and Repetitive Transcranial Magnetic Stimulation Combined With Robotic Rehabilitation on Ambulation and Lower Extremity Motor Function in Chronic Spinal Cord Injury Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Spinal Cord Injuries
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Lower extremity motor score
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
Comparison of different types of transcranial magnetic stimulation techniques which are intermittent theta burst stimulation (iTBS) and high frequency repetitive transcranial magnetic stimulation (rTMS) in patients with spinal cord injury
Detailed Description
iTBS lasts shorter than rTMS so that this technique comfortable than rTMS for both patients and also physicians. Aim of this study is to compare effectiveness of this techniques. If results are same, iTBS can be used instead of rTMS.
Investigators
Ayse Naz Kalem
Asist. Dr.
Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Eligibility Criteria
Inclusion Criteria
- •Incomplete spinal cord injury (ASIA C and D)
- •12 months after spinal cord injury
- •At least 10 meters walking independent or with canadian, walker or walking stick
- •Put signature to approved form
Exclusion Criteria
- •Epileptic seizure
- •Pacemaker
- •Pregnancy
- •Neurological disease different from spinal cord injury
- •Metalic implant in brain or scalp
- •Brain surgery
- •Orthopedic problem in lower extremity
- •Malignity
Outcomes
Primary Outcomes
Lower extremity motor score
Time Frame: Before treatment (0. week), finishing time of treatment (2.week), 4 weeks after finishing time of treatment (6.week)
Assesment of lower extremity key motor muscle function according to American Spinal Injury Association
Secondary Outcomes
- Spinal cord injury independence measurement III (SCIM III)(Before treatment (0. week), finishing time of treatment (2.week), 4 weeks after finishing time of treatment (6.week))
- 10 meter walking test(Before treatment (0. week), finishing time of treatment (2.week), 4 weeks after finishing time of treatment (6.week))
- Walking index for spinal cord injury II(Before treatment (0. week), finishing time of treatment (2.week), 4 weeks after finishing time of treatment (6.week))
- Time up and go test(Before treatment (0. week), finishing time of treatment (2.week), 4 weeks after finishing time of treatment (6.week))
- Motor evoked potential(Before treatment (0. week), finishing time of treatment (2.week), 4 weeks after finishing time of treatment (6.week))