S-Adenosylmethionine Therapy for Non-Alcoholic Steatohepatitis

Phase 3

Completed

• Conditions: Hepatitis

• Registration Number: NCT00108589
• Lead Sponsor: US Department of Veterans Affairs

Brief Summary

The purpose of this study is to examine the effect of S-adenosylmethionine therapy in those patients with non-alcoholic liver disease in the form of steatohepatitis (NASH). This will be accomplished by development of a database of these patients, all of whom will have biopsy documented NASH. A placebo controlled trial will then examine the effect of S-adenosylmethionine over time on clinical outcome in these patients. It is expected that this agent will slow or halt the progression of this disease.

Detailed Description

Not available

Study Timeline

• Study Start: 2004-01
• Study First Submitted: 2005-04-15
• Study First Submitted QC: 2005-04-15
• Study First Posted: 2005-04-18
• Study Completion: 2006-12
• Status Verified: 2007-05
• Last Update Submitted: 2009-01-20
• Last Update Posted: 2009-01-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: Not specified

Inclusion Criteria

• Men with biopsy proven non-alcoholic steatohepatitis from the liver disease clinic or referred from other physicians from the VAMC-Louisville.

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Trial Locations

Locations (1)

VA Medical Center; 🇺🇸 Louisville, Kentucky, United States