Randomized controlled clinical study to evaluate the efficacy of krishna mruttika lepa in the management of Vyanga with special refference to Mlasma
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Significant decrease in melasma pigmentation based on MASI Score.
研究概览
简要总结
Vyanga is a skin condition characterized by the presence of hyperpigmented patches on the face. It is considered a minor ailment in Ayurveda, categorized under "Kshudra Rogas."
The condition is marked by painless, bluish-black patches that typically appear symmetrically on both sides of the face as Niruja tanu ,shyava ,mukhamagatya mandalas.
In Ayurveda, Vyanga is believed to be caused by the vitiation of the Pitta and Vata doshas, which leads to the formation of these dark patches.
The condition is often associated with factors such as excessive sun exposure, hormonal changes, and stress. Ayurvedic treatment for Vyanga includes both internal and external therapies.
Internal treatments may involve the use of herbs and formulations that balance the doshas and purify the blood. External treatments often include the application of herbal pastes (Lepa),
oils (Abhyanga), and other topical remedies that help lighten the pigmentation and improve skin health.
krishna mruttika lepa is one of topical medicament ,taken here for the study of efficacy of krishna mruttika lepa in the management of vyanga.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Subjects diagnosed with Melasma chronicity less than 5 years of age.
- •2.Subjects fulfilling the diagnosed criteria of Melasma with clinical features of VYANGA .
排除标准
- •1 Individuals with hyper pigmentary disorders other than melasma 2 Females on oral contraceptive pills, pregnant women, lactating women 3 Hyperpigmentation since birth 4 individuals with endocrine disorders.
结局指标
主要结局
Significant decrease in melasma pigmentation based on MASI Score.
时间窗: 0TH Day-First Visit | 15TH Day -Second Visit | 30TH Day-Third visit | 45TH DAY-FOLLOW UP
Significant decrease in colour and number of lesions based on the arbitrary grading and fairness meter scale.
时间窗: 0TH Day-First Visit | 15TH Day -Second Visit | 30TH Day-Third visit | 45TH DAY-FOLLOW UP
次要结局
- generation of in depthanalysed data on different aspects of diseaseand its treatment.(45th day-follow up)
研究者
Dr Jasmeen S Akkalkot
Sri Sri College of Ayurvedic Science and Research Hospital