Comparative study of clinical and radiological outcomes of anterior cervical discectomy and fusion using ceramic cage or allograft spacer: a prospective randomized controlled trial.
- Conditions
- Diseases of the musculoskeletal system and connective tissue
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
? Symptoms and signs radiating to one or both arms (Pain, abnormality, or paralysis depending on the distribution of a particular neuromuscular muscle) or symptoms and signs related to acute or chronic myelopathy
? Conservative treatment (physical therapy, analgesic) for at least 8 weeks
? When it is possible to make an imaging diagnosis of one- or two-segment cervical disc herniation and osteophyte formation (from C3 to T1) associated with clinical symptoms and signs
? If you can and would like to participate in a clinical study
? With prior written consent of the patient or the patient's legal representative
?In case of uncertain or ambiguous symptoms
?Previous history of anterior or posterior cervical surgery
?When there is a risk of instability due to a height difference of 3 mm or more in the simple radiography of extension and flexion
?If the segment has severe kyphosis (more than 7 degrees)
?If the patient fails to take an MRI
?If there is only cervical pain without radiating symptoms or myelopathy
?If you have an infection
?If you have a metabolic disease or bone disease such as severe osteoporosis
?If there is a tumor or trauma of the cervical spine
?If there is a deformity in the spine
?Severe mental illness
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Visual Analogue Scale(VAS) score changes, NDI
- Secondary Outcome Measures
Name Time Method Radiological evaluation;WBC, Segmented neutrophil count, ESR, CRP;Pathologic reflex, Spurling sign, Lheimitte sign