Day 3 Embryo Cryopreservation: Metabolic and Viability Analysis

Not Applicable

Completed

• Conditions: Preservation of Supernumerary Embryos; Fertilization in Vitro
• Interventions: Procedure: Slow freezing; Procedure: Vitrification

• Registration Number: NCT00608010
• Lead Sponsor: V.K.V. American Hospital, Istanbul

Brief Summary

Embryo preservation through freezing plays a significant role in human assisted reproduction. It provides an opportunity for patients to have more than one attempt following an ovarian stimulation cycle, thereby decreasing the exposure of patients to exogenous gonadotrophins and improving cumulative pregnancy rates. The purpose of this study is to compare effectiveness of two different freezing methods.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-10
• Primary Completion: 2007-01
• Status Verified: 2008-01
• Study First Submitted: 2008-01-22
• Study First Submitted QC: 2008-02-05
• Last Update Submitted: 2008-02-05
• Study First Posted: 2008-02-06
• Last Update Posted: 2008-02-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 186

Inclusion Criteria

• ICSI with own gametes
• Couples who did not wish to cryopreserve their excess embryos for possible transfer in a future cyle
• Donating excess embryos for research purposes

Exclusion Criteria

• Embryos derived from surgically retrieved spermatozoa
• Blastocysts
• Embryos of low quality (Grade 3 or 4 according to Hardarson)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
2	Slow freezing	Slow freezing
1	Vitrification	Vitrification

Primary Outcome Measures

Name	Time	Method
Blastocyst development rate	3 days after thawing

Trial Locations

Locations (1)

American Hospital of Istanbul; 🇹🇷 Istanbul, Turkey