To comparison effect of intracameral adrenalin solution with concentration 1/10000 & 1/100000 on corneal endothelium and macular thickness after uneventful phacoemulsificatio

Phase 3

• Conditions: Cataracts.; Age-related nuclear cataract; H25.1

• Registration Number: IRCT20141019019581N5
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 16 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 210

Inclusion Criteria

210patients with cataract that refer to poostchi clinic

Exclusion Criteria

Patients with a history of eye surgery
Patients with a history of eye trauma
Patients with a history of diabetes mellitus and high eye pressure
Patients with a history of exfoliation syndrome
Patients with a history of corneal edema
Patients with a history of macular problems
Patients with any complications during the operation, including long phaco time, iris trauma and capsule rupture

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in macular thickness in the intervention groups. Timepoint: Before the intervention and three months later. Method of measurement: by specular device.

Secondary Outcome Measures

Name	Time	Method
Corneal endothelium cell density. Timepoint: Before operation and 3 month after operation. Method of measurement: Specular microscope.;The size of corneal endothelium cells. Timepoint: Before the operation and 3 months after the operation. Method of measurement: Specular microscope.;The shape of corneal endothelium cells. Timepoint: Before the operation and 3 months after the operation. Method of measurement: Specular microscope.