Predictive Value of Procalcitonin for Bacteremia in the ICU
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 170
- Locations
- 1
- Primary Endpoint
- The predictive value of procalcitonin in blood cultures on the ICU
Study Overview
Brief Summary
Association between plasma procalcitonin levels and positive blood cultures in critical illness patients in the ICU.
Detailed Description
Rationale: Association of procalcitonin levels and blood cultures in critical illness patients on the ICU.
Objective
Procalcitonin is an acute phase protein. As part of the acute phase response, procalcitonin is produced during sepsis. Previous research shows that procalcitonin is a biomarker for bloodstream infection. However, there is still little known about the value of procalcitonin in diagnostics for micro-organism underlying a sepsis in ICU patients. In modern practice, blood cultures are taken when a patient is septic to determine the responsible micro-organism. When procalcitonin is a predictive value for bacteremia in the ICU, the number of blood cultures can be reduced.
Study design: An observational cohort study intervention: for each patient in the ICU blood cultures were taken, the procalcitonin level was determined. During 6 months 150 patients will be included.
Main study parameters/endpoints: this study will examine the predictive value of procalcitonin in blood cultures on the ICU.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients admitted to the ICU
- •Age > 18 years
Exclusion Criteria
- •Hemodialysis/ Continuous Veno-Venous Hemofiltration
Outcomes
Primary Outcomes
The predictive value of procalcitonin in blood cultures on the ICU
Time Frame: 6 months
This study will examine the predictive value of procalcitonin on blood cultures on the ICU. A high value of procalcitonin is a predictor for bacteremia. The predictive value: procalcitonin. Primary outcome: bacteremia .
Secondary Outcomes
No secondary outcomes reported