Predictive Value of Procalcitonin for Bacteremia in the ICU
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Sepsis
- Sponsor
- Rijnstate Hospital
- Enrollment
- 170
- Locations
- 1
- Primary Endpoint
- The predictive value of procalcitonin in blood cultures on the ICU
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
Association between plasma procalcitonin levels and positive blood cultures in critical illness patients in the ICU.
Detailed Description
Rationale: Association of procalcitonin levels and blood cultures in critical illness patients on the ICU. Objective: Procalcitonin is an acute phase protein. As part of the acute phase response, procalcitonin is produced during sepsis. Previous research shows that procalcitonin is a biomarker for bloodstream infection. However, there is still little known about the value of procalcitonin in diagnostics for micro-organism underlying a sepsis in ICU patients. In modern practice, blood cultures are taken when a patient is septic to determine the responsible micro-organism. When procalcitonin is a predictive value for bacteremia in the ICU, the number of blood cultures can be reduced. Study design: An observational cohort study intervention: for each patient in the ICU blood cultures were taken, the procalcitonin level was determined. During 6 months 150 patients will be included. Main study parameters/endpoints: this study will examine the predictive value of procalcitonin in blood cultures on the ICU.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients admitted to the ICU
- •Age \> 18 years
Exclusion Criteria
- •Hemodialysis/ Continuous Veno-Venous Hemofiltration
Outcomes
Primary Outcomes
The predictive value of procalcitonin in blood cultures on the ICU
Time Frame: 6 months
This study will examine the predictive value of procalcitonin on blood cultures on the ICU. A high value of procalcitonin is a predictor for bacteremia. The predictive value: procalcitonin. Primary outcome: bacteremia .