SLEEP DISTURBANCES IN PATIENTS OF LIVER CIRRHOSIS WITH MINIMAL HEPATIC ENCEPHALOPATHY BEFORE AND AFTER LACTULOSE THERAPY

GB Pant Hospital0 个研究点目标入组 100 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•-Overt HE or history of overt HE
•- History of shunt surgery or transjuglar intrahepatic portosystemic shunt for portal hypertension
•-Electrolyte imbalance (Na <120 or >150meq and K <3.5 or >5.5meq) at the time of evaluation
•- Evidence of Infection ( Fever,TLC >11000) at the time of enrolment
•-History of recent use (within one month) of drugs affecting psychometric performances like benzodiazepines, antiepileptics, or psychotropic drugs
•- Hepatocellular carcinoma
•- Severe medical problems such as congestive heart failure, pulmonary disease, or neurological or psychiatric disorder that could influence quality-of-life measurement; and inability to
•perform neuropsychological tests .
•- History of alcohol intake within last one month.
•- History of intake of lactulose,rifaximin, L-ornithine-L-aspartate or probiotics in last one month.
•- History of GI bleed in last one month, spontaneous bacterial peritonitis (SBP) on prophylaxis or hepatorenal syndrome (HRS).
•- Patients of acute on chronic liver failure (ACLF).

发起方

GB Pant Hospital