Effect of Bicycle Ergometer Training in Thermoneutral and Lightly Cold Ambient Temperatures on Fat Tissue Amount and Metabolism in Overweight and Obese Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- concentration of serum adiponectin
研究概览
简要总结
The aim of this study is to investigate the effect of endurance training performed with a bicycle ergometer at different ambient temperatures on the amount of fat tissue and fat tissue metabolism in overweight and obese women.
详细描述
This study will examine the effects of 12 weeks of endurance training on a bicycle ergometer at thermoneutral and slightly cold ambient temperatures on body composition, subcutaneous and visceral fat tissue thickness, and levels of irisin, leptin, adiponectin, apelin, IL-6 and FGF-21 in the blood of overweight and obese women.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
The main outcome measures will be assessed by 3 different researchers . The researchers conducting the assessments will not know which group the participants are belongs to.
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Being female,
- •Being between 20-40 years old,
- •Having a BMI between 25 and 34.9,
- •Having a waist circumference greater than 80 cm,
- •Not having participated in any exercise program in the last 3 months ,
- •Not having experienced a change of more than 10% in body weight in the last 6 months.
排除标准
- •On a weight loss diet,
- •Having cancer, unstable heart disease, cerebrovascular disease, metabolic disease, diabetes, hypertension, psychiatric disorders, or other conditions or neurological disorders,
- •Having a musculoskeletal disorder or any disease/injury that may affect participation in exercise training,
- •Participating in regular physical activity (at least 150 minutes of moderate-intensity physical activity or 75 minutes of vigorous-intensity physical activity or an equivalent combination of both during the week),
- •Being pregnant or breastfeeding,
- •Having undergone surgery for the treatment of obesity,
- •Receiving pharmacological treatment for obesity. Participants who did not attend more than 20% of the endurance training program will be excluded from the study.
研究组 & 干预措施
Case group 1
participants trained in termoneutral ambient temperature
干预措施: endurance training with bicycle ergometer in termoneutral ambient temperature (Other)
Case group 2
participants trained in lightly cold ambient temperature
干预措施: endurance training with bicycle ergometer in lightly cold ambient temperature (Other)
control group
participants do not trained
结局指标
主要结局
concentration of serum adiponectin
时间窗: baseline/ through study completion, an average 3 months
assesed with blood analysis
Waist circumference Waist hip ratio
时间窗: baseline/ through study completion, an average 3 months
Waist circumference will be measured with a tape measure.
concentration of serum irisin
时间窗: baseline/ through study completion, an average 3 months
assesed with blood analysis
concentration of serum apelin
时间窗: baseline/ through study completion, an average 3 months
assesed with blood analysis
concentration of serum IL-6
时间窗: baseline/ through study completion, an average 3 months
assesed with blood analysis
rate of BMI
时间窗: baseline/ through study completion, an average 3 months
assesed with height and body weight
analysis of biyoelectric impedans Bioelectrical impedance analysis
时间窗: baseline/ through study completion, an average 3 months
assesed with with a Tanita BC 418 brand device.
rate of subcutaneous and visceral adipose tissue thickness
时间窗: baseline/ through study completion, an average 3 months
assesed with Ultrasonography
次要结局
未报告次要终点
研究者
Şule ŞİMŞEK
Principal İnvestigator
Pamukkale University