The Efficacy of Shear-wave Elastography-guided Biopsy for Diagnosis in Pleural Disease: a Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 234
- 试验地点
- 1
- 主要终点
- The diagnostic yield of the two groups
研究概览
简要总结
To investigate the information from shear-wave elastography on pleural tissues will improve the diagnosis of pleural diseases, as to increase the diagnostic yield in ultrasound-guided transthoracic pleura biopsy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with radiographic evidence of pleural disease
排除标准
- •Age < 18 y/o
- •Patients who cannot hold their breath for 5 seconds
研究组 & 干预措施
Shear-wave elastography-guided
based on the shear-wave elastography, the area with the highest elasticity value will be the target area to perform pleural biopsy for at least 6 times
干预措施: different types of ultrasound technique (Procedure)
B-mode ultrasound-guided
based on the B-mode transthoracic ultrasound, the area with the maximal thickness will be the target area to perform pleural biopsy for at least 6 times
干预措施: different types of ultrasound technique (Procedure)
结局指标
主要结局
The diagnostic yield of the two groups
时间窗: 6 months
the pathology of pleural biopsies will be interpreted by cytopathologists
次要结局
- Procedure time(1 day)
- the rate of pneumothorax & hemothorax(1 day)