Cost-effectiveness analysis of oral paracetamol and ibuprofen for treating pain after soft tissue limb injuries: double-blind, randomised controlled trial

Chinese University of Hong Kong (Hong Kong)0 个研究点目标入组 782 人开始时间: 2007年10月19日最近更新: 2021年7月26日

试验速览

2018 Results article in https://pubmed.ncbi.nlm.nih.gov/29408866/ (added 15/07/2021)

•All patients greater than 16 years presenting to the Emergency Department (ED) with isolated soft tissue injury without significant fracture between 9 am to 5 pm, Monday to Friday.

•Patients will be excluded if there is:
•1. A history of peptic ulceration or haemorrhage
•2. Recent anticoagulation
•3. Pregnancy
•4. Adverse reaction to paracetamol or ibuprofen
•5. Renal or cardiac failure
•6. Hepatic problems
•7. Rectal bleeding
•8. Chronic Non-Steriodal Anti-Inflammatory Drug (NSAID) consumption
•10. Chronic obstructive pulmonary disease
•11. Chronic pain syndromes
•12. Prior treatment with analgesia for the same injury
•Patients will also be excluded if they have a physical, visual or cognitive impairment making use of the visual analogue scale unreliable.

发起方

Chinese University of Hong Kong (Hong Kong)