Cost-effectiveness analysis of oral paracetamol and ibuprofen for treating pain after soft tissue limb injuries: double-blind, randomised controlled trial

Not Applicable

Completed

• Conditions: Soft Tissue Injuries; Injury, Occupational Diseases, Poisoning

• Registration Number: ISRCTN94738550
• Lead Sponsor: Chinese University of Hong Kong (Hong Kong)

Brief Summary

2018 Results article in https://pubmed.ncbi.nlm.nih.gov/29408866/ (added 15/07/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-10-19
• Study Completion: 2007-12-31
• Last Update Posted: 26 July 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 782

Inclusion Criteria

All patients greater than 16 years presenting to the Emergency Department (ED) with isolated soft tissue injury without significant fracture between 9 am to 5 pm, Monday to Friday.

Exclusion Criteria

Patients will be excluded if there is:
1. A history of peptic ulceration or haemorrhage
2. Recent anticoagulation
3. Pregnancy
4. Adverse reaction to paracetamol or ibuprofen
5. Renal or cardiac failure
6. Hepatic problems
7. Rectal bleeding
8. Chronic Non-Steriodal Anti-Inflammatory Drug (NSAID) consumption
9. Asthma
10. Chronic obstructive pulmonary disease
11. Chronic pain syndromes
12. Prior treatment with analgesia for the same injury

Patients will also be excluded if they have a physical, visual or cognitive impairment making use of the visual analogue scale unreliable.

Study & Design

• Study Type: Interventional
• Study Design: Not specified