The effectiveness and cost-effectiveness of arthroscopic lavage in the treatment of osteoarthritis of the knee

Completed

Conditions: Osteoarthritis of the knee
Musculoskeletal Diseases
Osteoarthritis

Registration Number: ISRCTN02328576

Lead Sponsor: Department of Health (UK)

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 70

Inclusion Criteria

1. Adults (18 years or older) with radiological evidence of osteoarthritis (OA) of the knee who might routinely be considered for arthroscopic lavage
2. Fit for general anaesthetic (American Society of Anesthesiologists [ASA] grade 1 and 2)
3. Able to give informed consent

Exclusion Criteria

1. Patients for whom the orthopaedic surgeon judges that arthroscopic lavage is clearly indicated
2. Patients for whom arthroplasty is clearly indicated
3. Clear contraindication to general anaesthesia
4. Inability to fill in follow-up questionnaires

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. To examine whether the trial processes as currently planned are appropriate, feasible and acceptable to patients, clinicians and the trial office staff<br>2. To quantify the throughput of eligible patients<br>3. To quantify the number of patients approached and the proportion of patients who would accept randomisation to the trial<br>4. To examine the acceptability of the trial information material to patients

Secondary Outcome Measures

Name	Time	Method
The secondary research outcomes of the main trial (in which we anticipate the pilot patients' data being included) are:<br>1. General quality of life as measured by 12-item short form questionnaire (SF-12)<br>2. Patient utility as measured by EQ5D<br>3. Non-steroidal anti-inflammatory drug (NSAID) or analgesic use<br>4. Use of other treatments outside the trial interventions<br>5. Use and cost of health services<br>6. Cost-effectiveness - incremental cost per quality adjusted life year gained