Optical Nerve Sheath Changes During Head Down Laparoscopy
Completed
- Conditions
- Intracranial HypertensionPneumoperitoneumBrain EdemaSurgery, Laparoscopic
- Registration Number
- NCT03957837
- Lead Sponsor
- ASST Fatebenefratelli Sacco
- Brief Summary
Patient undergoing laparoscopic radical prostatectomy in steep trendelenburg position are at risk to develop complication from brain edema.
Ultrasound assessment of optical nerve sheath diameter is a simply, non-invasive method to estimate the increase of intracranial pressure. It is unknown how optical nerve sheath diameter changes after prolonged head down position.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 20
Inclusion Criteria
- patients undergoing elective laparoscopic prostatectomy in steep Trendelenburg position
- American Society of Anesthesiologists risk I-III
Exclusion Criteria
- Age <18 or >70 years
- American Society of Anesthesiologists risk >III
- Assumption of beta-2-blockers, diuretics
- Heart failure with NYHA class ≥ IIb
- Diabetes with ocular (i.e. retinopathy), neurologic (i.e. peripheral neuropathy), or renal complications
- History of cardiac surgery, thoracic surgery, suprainguinal vascular surgery, head surgery, ocular surgery, stroke, hydrocephalus.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Optical nerve sheath diameter changes during steep Trendelenburg position 2 months changes of optical nerve sheath diameter in millimeters measured by ultrasound in patients undergoing laparoscopic radical prostatectomy and in healthy volunteers
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
ASST Fatebenefratelli Sacco, Luigi Sacco Hospital
🇮🇹Milan, Italy
ASST Fatebenefratelli Sacco, Luigi Sacco Hospital🇮🇹Milan, Italy