Effectiveness of MIST (minimally invasive surfactant therapy) under bronchoscopy in treating neonatal respiratory distress syndrome
Not Applicable
- Conditions
- eonatal respiratory distress syndrome
- Registration Number
- JPRN-UMIN000021785
- Lead Sponsor
- Tokyo Women's Medical University Adachi Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
Patients fulfilling any of the following criteria will be excluded 1. Patients with severe birth asphyxia 2. Patients with multiple malformation syndrome, or other suspected underlying diseases 3. Patients needing vasoactive drugs 4. Patients with tendency to bleed 5. Patients with congenital infections 6. Patients thought to be inappropriate for the study by the supervising physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Short term prognosis of respiration in patients treated with bronchoscopic MIST. Short term prognosis of respiration includes the following 1. Days under mechanical ventilation 2. Days under supplemental oxygen 3. Incidence of airway diseases 4. Need for endotracheal intubation or additional surfactant
- Secondary Outcome Measures
Name Time Method 1. Morbidity of diseases often seen in premature infants(intraventricular hemorrhage, pneumothorax, patent ductus arteriosus, bronchopulmonary dysplasia, sepsis, necrotizing enterocolitis) 2. Length of hospitalization, mortality rate